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The American Diabetes Association now recommends GLP-1 RAs for patients with established ASCVD regardless of their A1C and regardless of if the patient is taking metformin, the historically first line medication for T2DM [38]

98% is considered research-grade for both peptides, but 99% purity is strongly preferred for combination repair studies, wound healing experiments, musculoskeletal repair research, cardiovascular biology, and neuroprotection studies where compound purity of both peptides directly affects biological activity measurements and experimental reproducibility

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Tirzepatide combines GLP-1 activity with GIP receptor agonism

Am J Sports Med 1999;27:363369