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While the findings dont establish a clear causal link between GLP-1 drugs and eye disease, experts say theres still reason for caution

Recently these GLP-1 drugs have been marketed beyond obesity management but also for perimenopause/menopause weight gain management, cosmetic weight loss, and microdosing for achieving/maintaining optimal weight

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The ATTAIN-1 trial reported a mean change in body weight at 72 weeks of -11.2% with the highest dose of orforglipron 36 mg compared to -2.1% with placebo in adults with obesity or overweight and at least one weight-related comorbidity