The trick is to make sure its cooked for a really long time so all of the collagen soaks out of the bones, says Gellman
Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies
faulty ubiquination is linked to the development of cancer, metabolic syndromes, neurodegenerative diseases, autoimmunity, inflammatory disorders, infection and muscle dystrophies. 107 With many chemicals binding to lysine residues and thereby limiting their availability, extra lysine is likely needed for these diseases
Studies show it can act as both a NO promoter and stabilizer depending on the physiological context, helping maintain optimal blood flow to injured areas
Shao K, Zhang Y, Ding N, Huang S, Wu J, Li J, et al