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After the 26-week treatment period, the mean percentage of weight reduction from baseline was greater with all doses of cagrilintide (0.34.5 mg, 6.0%10.8%) versus placebo (3.0%)

Methods Standard protocol approvals and registrations The present systematic review and meta-analysis is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta- Analyses (PRISMA) statement

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Those on semaglutide 2.4 mg lost an average of 15.3% of their body weight over 68 weeks, compared to just 2.6% in the placebo group