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doi: 10.1186/s12937-018-0351-0

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These medications carry a boxed warning about thyroid C-cell tumors observed in rodent studies and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Two other studies involving 206 exposed pregnancies and 267 comparator pregnancies showed no evidence of an association with spontaneous abortion (OR 0.95

others develop more persistent bloating that affects daily comfort