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Significant improvements in the severity and frequency of specific depression-related symptoms only occurred after four weeks of treatment, suggesting that a longer treatment period might be needed to uncover the antidepressant effects of curcumin (100, 101)

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Antioxid Redox Signal 15:15831606 Ray PD, Huang B-W, Tsuji Y (2012) Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

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Its likely youre already familiar with some types of these medications, including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)