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Acarbose could consistently contribute to the glucose reduction for 35 years ( The main mechanism of acarbose to optimize the glucose metabolism is the role in slowing the postprandial glucose absorption, which is almost independent from the insulin secretion or its action ( Acarbose and DPP-4is were reported to have a higher efficacy in Eastern patients than in the Western counterparts (34)

En 1992, el Servicio de Salud Pblica de los Estados Unidos a travs del Center for Disease Control and Prevention (CDC) recomend que todas las mujeres con posibilidades de embarazo ingirieran una dosis de cido flico de 0,4 mg al da (4)

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