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TSCI imposes a significant personal and socioeconomic burden due to its poor prognosis and high healthcare costs

The C-terminal redox centre of hTrxR1, located on a flexible arm, has been expected to act as an electron shuttle between the buried N-terminal dithiol and the substrate 16,24

Combined with WBCILs WHO-GMP certified manufacturing and 64+ years of pharmaceutical API expertise, this is a glutathione ingredient that holds up under regulatory scrutiny and delivers consistent batch-to-batch performance at commercial scale

Indeed, 79.3% of NDP52 KO HeLa cells, in which OPTN is the lone mitophagy adaptor, were mitophagy-positive after 5 hrs with AO (Fig 6b, c)

This tripeptide compound made up of amino acids - L-glutamate, L-cysteine and glycine - plays a key role in protecting cells from harmful free radicals and oxidative stress