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Med-Safe in NZ, FDA in USA) use the rate and extent of absorption to judge if a generic drug is bioequivalent to the originator product

The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]

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