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Matoba et al., 2023)
Collapse of HF-IP is one of the most widely accepted theories about the pathogenesis of alopecia areata
In some cases, temporary dose reduction or slower titration may allow your body to adapt while minimizing gastrointestinal side effects
But also, other important metabolic regulators, such as AMP-activated kinase (AMPK), can be activated to counteract energy deprivation
This is followed by the generation of glutathione and activation of glutathione peroxidase 4, which plays a critical role in protecting cells from ferroptosis
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