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28,29 While not associated with clinical benefit in HFrEF, recently, these drugs have been studied in patients with HFpEF demonstrating improvements in clinical outcomes such as health-related quality of life (STEP-HFpEF) as well as reductions in cardiovascular death and HF events (SUMMIT)

My hips had spread

All other FDA-approved GLP-1 agonists only exert effects on the GLP-1 receptor [5]

most see benefits in 46 weeks with consistent use

Availability of data and materials The datasets used and analyzed during the current study are available from the corresponding author upon a reasonable request