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Compound identity at a glance Name: Retatrutide INN: LY3437943 Class: Triple incretin receptor agonist Structure: 39-amino-acid synthetic peptide Dosing interval: Once weekly (research protocols) Developer: Eli Lilly For the full molecular reference (molecular formula, molecular weight, CAS number and the 39-amino-acid sequence) see the Retatrutide molecular profile

Because GLP-1s delay gastric emptying, they can increase residual gastric content raising the risk of pulmonary aspiration of gastric contents at induction and throughout an anesthetic even if a patient has been appropriately adherent to current NPO guidelines

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2011;3:CD007749

Suzuki S, Oura T, Takeuchi M, Boye KS