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Shanzhiside methyl ester, the main active component of Lamiophlomis rotata, also significantly reduced pain sensitivity in neuropathic rats over time without leading to tolerance [102]

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FIGURE 6: PATENT TYPES FOR SEMAGLUTIDE FIGURE 7: ANNUAL PATENT FILINGS FOR SEMAGLUTIDE FIGURE 8: DURATION OF PATENT PROTECTION FOR SEMAGLUTIDE TIRZEPATIDE Tirzepatide, marketed as Mounjaro for diabetes and Zepbound for weight loss, is a newer entrant to the GLP-1 receptor agonist market