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The accumulation of AGEs in the body irreversibly modifies the structure and function of proteins such as collagen and elastin

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Orlistat is only recommended for use in children in exceptional circumstances Currently, only one agent (orlistat) has FDA approval for the treatment of obesity among adolescents 12-16 years of age [42], for example if a child is severely obese and has an obesityrelated complication such as a problem with bones or joints or sleep apnea

Many people may notice a decrease in appetite as the medication delays gastric emptying and increases a feeling of fullness