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Not directly it isn't a diuretic

Wang L, Berger NA, Kaelber DC, Xu R

While well controlled studies are not yet available, the use of xylazine as a street drug has been associated with the development of severe wounds that erupt with a scaly dead tissue called eschar , which if left untreated can result in the need for amputation

[DOI] [PubMed] [Google Scholar] Hastings TG

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