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Ethical treatment under GCP not only protects patients but also upholds the integrity of the research, ensuring that participants are respected and treated with care throughout the trial process

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Although the drug is not specifically approved by the FDA for medical weight loss, some studies have shown that it may have potential benefits for weight loss as a secondary effect of the drugs primary purpose

The compound was first reported in Al-Obeidi, Castrucci, Hadley, and Hruby, J Med Chem 32 (12):255561 (1989) (PMID 2555512), building on the earlier open-chain superpotent precursor [Nle, D-Phe]--MSH reported by Sawyer, Sanfilippo, Hruby, Engel, Heward, Burnett, and Hadley in PNAS 77 (10):57548 (1980) (PMID 6777774)