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Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent

Inhibiting core enzymes of DNL, including citrate/isocitrate carrier (CIC), ATP-citrate lyase (ACLY), acetyl-CoA carboxylase (ACC) and fatty acid synthase (FAS), represents an attractive therapeutic strategy

Statistics Differences among the time points were evaluated using one-way analysis of variance (ANOVA) followed by Turkeys test using GraphPad Prism 6 (GraphPad Software, San Diego, CA, USA)

Other investigations examine cellular signaling, circadian regulation, and intracellular physiology

Isotopic tracing coupled with super-resolution imaging now permits real-time tracking of Kla spatiotemporal dynamics in living systems, revealing its metabolic regulation and subcellular distribution