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Abstract An increasing body of evidence highlights the strong potential for a diet rich in fruit and vegetables to delay, and often prevent, the onset of chronic diseases, including cardiometabolic, neurological, and musculoskeletal conditions, and certain cancers

associated with B12 deficiency with long-term use (per ADA 2026, monitor B12 periodically) SGLT-2 inhibitors (empagliflozin, dapagliflozin, canagliflozin): Glucosuria mechanism

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