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& Kusakabe, M

Antidiabetic agents The definition of MASLD includes hepatic steatosis and meets at least one of three criteria: T2DM, obesity, or metabolic disorder

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Patients with genetic profiles indicating heightened GLP-1 sensitivity may benefit from lower starting doses or extended dose-escalation timelines that minimize early adjustment symptoms like headaches

These adverse effects often improve with time or can be managed through dose adjustments, dietary modifications, or symptomatic treatment