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While missing a single period is not typically harmful, consistently irregular or missed periods should be evaluated by a healthcare provider to address any underlying issues and prevent potential health problems

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This could be particularly important for women whose estradiol levels are abnormal, perhaps as a result of ovarian dysfunction, or whose estradiol levels drop, as part of the normal estradiol decline during menopause

Haider Z, et al

That kind of range is broad enough for a new skincare brand to build a coherent entry-level collection, but still focused enough that the company can streamline operations and present a simpler buying experience