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They may advise withholding your next dose until symptoms resolve to prevent acute kidney injury, particularly if you have pre-existing renal impairment

About one-third of participants lost 20% or more of their starting weight

It can influence pro-inflammatory molecules like interleukin-6 (IL-6) and TNF-alpha, which are linked to prolonged inflammation in injury models

NICE guidance (TA875) recommends semaglutide 2.4 mg for weight management through specialist weight management services, with specific BMI thresholds and typically limited to 2 years of treatment on the NHS