The antioxidant function of GSH has led to speculation about its therapeutic role in numerous chronic diseases characterized by altered redox balance and reduced GSH levels, including, for instance, neurodegenerative disorders, cancer, and chronic liver diseases
In good agreement with this finding, our analysis of the selected transcripts characterizing thiamine-dependent metabolism, shows an overall increase in the transcripts for the related proteins (Figures 4, 5)
However, it must be pointed out that malignant transformation takes time, and if the patient goes to an oncosurgeon or oncologist, it may not always reflect as long-term complications in dermatological practice
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71 Moreover, GLP-1RAs have demonstrated considerable therapeutic promise in animal models of both PD and AD