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The GLP-1 analogs Liraglutide and Semaglutide reduce atherosclerosis in ApoE(-/-) and LDLr(-/-) mice by a mechanism that includes inflammatory pathways

Overall, C-terminal truncation of Syn results in a loss-of-function and a gain-of-toxicity

Patients with comorbid depression may benefit from bupropion's mood-increasing effects, though this shouldn't replace dedicated depression treatment

The vaccines accelerated approval is based partly on the Phase III STRIDE-3 study, in which Capvaxive was non-inferior to a commercially available 20-valent comparator vaccine