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It increases thermogenesis

Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans

Opioids Opioids are drugs that can be prescribed by doctors to treat pain, such as oxycodone (OxyContin), hydrocodone (Vicodin), morphine (Arymo), and methadone (Dolophine), according to the Centers for Disease Control and Prevention (CDC)

It works by imitating the effects of a hormone called GLP-1 (glucagon-like peptide-1), which the body naturally produces in the gut

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