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Limited long-term human data prevents definitive safety conclusions, but decades of research suggest low risk with proper use

The RP is the major side effect of thoracic radiotherapy in lung and breast cancer patients [61, 62]

42 Although GLP-1RA and dipeptidyl peptidase-4 inhibitors (DPP-4i) also confer some cardiovascular benefits, they do not offer a significant advantage for reducing the hospitalization of HF in patients with diabetes (Table 1)