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Nevertheless, concerning case reports and retrospective studies have emerged in 2023 of undigested gastric contents in sedated/anaesthetised patients undergoing elective endoscopy with unprotected airways: Klein and Hobai (2023) published a case report of a patient taking semaglutide for weight loss who experienced pulmonary aspiration from undigested food content identified during routine gastroscopy, despite fasting 18hr prior to the procedure

What starting dose is safest given your current medication list

Interestingly, seven of the 11 patients developing HT in the first 48 h had recanalization in the first 12 h, while none of the patients with HT beyond 48 h had early recanalization (110)

MicroRNA-126-3p/-5p overexpression attenuates blood-brain barrier disruption in a mouse model of middle cerebral artery occlusion

Until official regulatory approval is granted, there is no approved maximum dose for clinical use