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A new analysis from the landmark SELECT trial reveals that semaglutide can quickly reduce the risk of heart attacks and other serious cardiovascular events in people with overweight or obesity who already have heart disease, even if they do not have diabetes

Some SSRIsparticularly paroxetinehave been associated with weight gain over long-term use

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Weight loss, however, may be slightly slower compared to non-diabetic populations, likely due to the metabolic resistance created by chronic insulin dysregulation and the weight gain effects of concurrent diabetes medications like sulfonylureas or insulin

23:1063-1065 [PubMed: 33319468] 232