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BMJ 2024;387:e080340.ArticlePubMedPMC 24
These may include leaky gut, chronic inflammation, toxin exposure, infections, nutrient deficiencies, and long-term stress
This conversion is a major metabolic checkpoint
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Effects when activated: Stimulate insulin secretion from pancreatic beta cells Promote fat storage in adipose tissue Enhance bone formation May have effects on cognitive function and neuroprotection Key Differences: Hormone specificity: GLP-1 receptors are activated by GLP-1, while GIP receptors are activated by GIP
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