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I., Waldstreicher, J

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[59] reported that individuals at stages IIIV of chronic kidney disease exhibit significantly reduced urine levels of S-adenosylmethionine and SAM/S-adenosylhomocysteine ratio, as well as a decreased cysteine/homocysteine ratio in blood plasma in comparison to patients at stage II of CKD

however, during treatment, an increase in plasma triglyceride levels was recorded, with 16 patients having levels of more than 500 mg/dL