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However, species-specific differences (for example, in metabolism and toxicity) impact understanding of which concepts are universal and which are species-specific, making the translation of potential therapeutic targets into effective human therapies a substantial challenge

This only makes the situation worse, as the high GH levels only further increase the already elevated insulin-like growth factor-1 (IGF-1) concentrations

Microbiota controls the homeostasis of glial cells in the gut lamina propria

J Endocrinol Invest 44(9):18271835

Ramaekers et al., observed lower levels of 5-MTFH, the active form of folic acid, in the cerebrospinal fluid (CSF) in ASD patients