The FDA has approved injectable and oral GLP-1 medications (such as Wegovy, Ozempic, and Zepbound), but no transdermal patch products
As cathepsin B has been previously reported to play a significant role in promoting cell death during liver injury ( per se a role in APAP hepatotoxicity (Woolbright et al., 2012)
Heres whats happening in real life: Rapid weight loss = volume loss in the face Volume loss = sagging or hollow appearance People then seek skin tightening or rejuvenation treatments Ironically, GLP-1 medications may increase demand for professional facial treatments
And if you ever are willing to come out to Yale and do a series of events like we did with Mandy [Cohen], I am all in. Eric Topol: No, I would love to do that. Howard Forman: Thank you. Harlan Krumholz: Well even try to sell some books if you do. Eric Topol: All right
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