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Moreover, excessive fission disrupts mitochondrial membrane potential, causes mitochondrial damage, and impairs both cellular energy metabolism and iron homeostasis, further sensitizing cells to ferroptosis [56]

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These can be mild nausea, feeling tired, and trouble with constipation

As we delve further into semaglutides role in the management of diabetes and obesity, the balance between its benefits and risks remains a focal point of discussion among healthcare providers and researchers alike

On the pathological side, intestinal dysbiosis and compromised barrier integrity may allow pathogenic bacteria (e.g., Fusobacterium ) to enter the systemic circulation