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Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4):A randomised, double-blind, phase 3a trial [published correction appears in Lancet 2019;394:e1] Lancet

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Notes from GLP-1 Match Note: as of October 2025, their expected lead time after getting your prescription sent to the pharmacy is 5-7 business days plus 1 day for transit

PIONEER 5 and 8 also showed efficacy and safety of oral semaglutide as a second- and third-line drug.[15,16,17,18,19,20,21,22,30,31] Thus, oral semaglutide can be used across the spectrum of diabetes as a first-, second- and third-line drug

Injectable (Ozempic/Wegovy): Administered once a week using a prefilled pen