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It is not produced naturally by our bodies, so it must be derived from food

If you feel satisfied after half your usual portion, stop eatingyour appetite suppression is working as intended

However, in the exenatide treatment group, the primary outcome rate was 61.2% (n=170), compared to 56.7% in the standard treatment group (n=171), with an adjusted ratio of 1.22 [95% CI, 0.79-1.88] (P=0.38)., which meant that the proportion of subjects who achieved the desired effect in exenatide treatment group was higher (110)

BUT only a small part of the population can afford them

One more thing to consider is whether or not oral GLP-1 agonists obtain FDA approval for obesity