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Pharmaceutical GLP-1 agonists produce sustained receptor activation at levels far exceeding what natural GLP-1 achieves, even after meals

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Similarly, genetically engineering FOXP3 into CAR-T cells optimizes their intrinsic lipid utilization, conferring superior persistence and therapeutic efficacy [174]

ACS Medicinal Chemistry Letters, 7 (5), 520524

Glutathione-Independent Ferroptosis Although described since the beginning to be the main actor of ferroptosis inhibition, it has been recently described that the cysteine-GSH-GPx4 axis can be, at least in part, dispensable