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Notably, at 6 M, curcumin synergistically reduces interleukin-1(IL-1)/IL-6 secretion by 50% through inhibition of extracellular signal-regulated kinases/c-Jun N-terminal kinases (ERK/JNK) phosphorylation (EC50 = 8.4 M) and targeting of the signal transducer and activator of transcription 3 src homology 2 (STAT3 SH2) domain (G = 7.1 kcal/mol) (Peng et al., 2021

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

We screen carefully for contraindications and consider your complete health profile, including cardiovascular risk and history of type 2 diabetes