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Average loss: 1-2kg over 12 weeks

The dosing and the duration shift with the operation

In comparison to CsA, tacrolimus offers greater potency and a more favorable side-effect profile, leading to increased long-term survival in patients (Yang, 2010)

Disruption of the antigen processing machinery (APM) IGF-1 consistently downregulated TAP1, TAP2, ERAP1, and 2-microglobulin (2M)key components required for peptide transport and loading onto MHC-I complexes