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The World Health Organization states that all forms of tobacco use are harmful and that there is no safe level of exposure to tobacco

And, despite being produced from cellulose fibers, the material has been chemically altered to form a polymer that stubbornly resists natural decomposition

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Importantly, we used scRNA-seq to deconstruct smoking effects on the epithelium to the cell-type level, which we have then reassembled into a comprehensive model of how smoking modifies epithelial function as a whole (Fig

Descriptive statistics were computed and reported as mean standard deviation (SD) for age, gender, height, weight, BMI and exhaled CO at each time point