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Archives of Environmental Contamination and Toxicology 50, 205212, 10.1007/s00244-004-0132-y (2006)

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The mechanism underlying the association between betel nut chewing and HCC may also be related to safrole, which may be the reactive agent responsible for hepatocarcinogenesis 46

Results Nicotine-induced neutrophils infiltrate in premetastatic lungs and enhance metastasis To assess the association between cigarette smoking and the development of pulmonary metastasis among breast cancer patients, we performed retrospective pan-analysis of three previously reported breast cancer cohorts 53,54,55,58 with smoking history that comprised a total of 1077 cancer patients