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Nicotine pouches should only be used by people trying to quit smoking or anyone who already makes use of other nicotine products like vapes or gum

[4] OX/ROS could react with other chemicals in the e-cigarette vapor because they are highly reactive, causing alterations its chemical composition

[33] With all these influences, cessation can be very difficult for women

Combined with mass cigarette advertising, including the infamous 1940s More doctors smoke Camel than any other cigarette which successfully distracted the population from early concerns about harm, cheap cigarettes saw smoking prevalence skyrocket globally