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Although the circulating LH levels of the rhGH rats did not differ from those of the control rats on PND 24 or 31, the pituitary Lhb mRNA levels in the rhGH rats were lower than those in the control rats on PNDs 24 and 31, suggesting that elevated testosterone levels provide negative feedback for the expression of pituitary Lhb

Excess B12 from high oral doses is primarily excreted through urine, which contributes to its low toxicity profile

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To maintain enough H 2 O levels for hormone production without causing oxidative damage, GPX activity is necessary [16]

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