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Electronic cigarettes increase EPCs

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This effect was greatest in the lung cells, but was also noticeable in the mouth, where every cell had an average of 23 mutations per pack year, as well as the bladder and the liver, where cells picked up 18 and six mutations respectively for each year of such excessive smoking

Around half of the children (49%) had a history of active smoking by middle age, and just over 5% of them had developed COPD by this time point, as assessed by spirometry