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It is also possible that some of the effects of GLP-1 agonists on food intake may be mediated by interaction with sensory afferent neurones of the vagus nerves in the gastrointestinal tract

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A comparative safety review between GLP-1 receptor agonists and SGLT2 inhibitors for diabetes treatment

Clinical Implications These findings raise the possibility that early differences in gut hormone trajectories (particularly attenuated GLP-1 and GIP responses) may be linked to WR risk following LSG in adolescents

Younger researchers might benefit from lower doses focused on maintenance rather than correction