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You should contact your GP or diabetes care team if: Urinary frequency significantly increases or becomes bothersome You experience pain, burning, or discomfort when urinating Urine appears cloudy, bloody, or has a strong odour You develop excessive thirst alongside increased urination You experience symptoms of dehydration (dizziness, dry mouth, dark urine) For urgent but non-emergency concerns, contact NHS 111 for advice

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1 The dopaminergic system comprises four functionally and anatomically interconnected pathways, including the mesolimbic, nigrostriatal, mesocortical, and tuberoinfundibular pathways

Journal of Pineal Research, 46(4), 357-364