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Abstract G protein-coupled receptors are important drug targets that engage and activate signaling transducers in multiple cellular compartments

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Biochim Biophys Acta 1271:3542 Moraitis C, Curran BPG (2010) Differential effects of hydrogen peroxide and ascorbic acid on the aerobic thermosensitivity of yeast cells grown under aerobic and anoxic conditions

These white blood cells are upregulated and activated to produce pro-inflammatory cytokines and prostaglandins which activate nerves and trigger the upregulation of nociceptive transient receptor potential (TRP) cation channels [92,94]

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