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The characteristics of the sample, at the time of their most recent hospitalisation, are presented in Table 3

Since nicotine is a weak base (pKa=8.0), at a higher pH, a larger portion of nicotine is unprotonated (free-base) and nicotine is more volatile.62 Because of higher pH, a significant proportion of nicotine is present in the gas phase of inhaled aerosol

Common tobacco fertilizer application methods include broadcast spreading for pre-plant and band placement for side-dress treatments