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Plasmid DNA was purified using the NucleoBond Xtra Maxi kit (Macherey-Nagel, Germany) and sequenced prior to use (Centre for Genomics, Proteomics and Metabolomics, University of Auckland)

This knowledge led to the hypothesis that increased levels of Gsto2 in iSPNs can disrupt AA homeostasis, leading to changes in TH protein levels and increased DA synthesis in striatal projecting mDA neurons that potentially express no or low TH in the adult brain

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