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m6A Demethylase FTO-mediated upregulation of BAP1 induces neuronal ferroptosis via the p53/SLC7A11 axis in the MPP+/MPTP-induced Parkinsons Disease model

The video covers key topics like: - Proarrhythmic mechanisms (slow conduction, repolarization prolongation, calcium overload) - State-dependent drug binding (active, inactive, resting states) - Clinical applications and warnings for Class 1C, 1B, and Class 3 agents A great review for anyone in #Cardiology, #CriticalCare, or #InternalMedicine

SLU-PP-332 was rationally designed and synthesized to be an ERR pan-agonist

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