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Fewer systemic side-effects compared to hGH Because AOD 9604 does not significantly elevate IGF-1 or impair glucose/insulin regulation (in trials), it may carry lower risk of some growth hormone-associated adverse effects
Gallbladder events rise modestly, especially with rapid loss. Less common signals include skin dysesthesia, which is now on the label, and a small thyroid-cancer association in two population studies with a tiny absolute event rate. Depression and suicidality remain unproven
However, they do not contain actual GLP-1 or its direct synthetic counterparts, which are the basis of prescription GLP-1 receptor agonist medications
It is important to think about other possible causes such as age, physical activity, previous injuries, or arthritis