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An oral melanotic macule is a small, flat, well-defined brown to black patch in the mouth caused by harmless extra melanin in the lining

in rats with abdominal aorta anastomosis BPC 157 both prevents thrombotic clot formation and destroys already formed thrombosis (40) and also, after amputation, BPC 157 reduces bleeding time and thrombocytopenia after heparin, warfarin or aspirin administration (41)

Seek immediate medical attention for Signs of severe allergic reaction: difficulty breathing, swelling of the face or throat, rapid heartbeat, severe dizziness

It depends on your desired concentration

However, long-term human safety data from controlled clinical trials is limited